FAM160A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM160A2 mutation is significantly associated with the RNA expression of many other genes, with 2,059 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM160A2-associated genes across cancer lineages are CBARP, TSPOAP1, and ZWINT. Each is linked with FAM160A2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM160A2-to-partner and partner-to-FAM160A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBARP grouped by FAM160A2-low versus FAM160A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160A2→partner) and Y-score (partner→FAM160A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCBARP →+0.609+2.222<.001<.00134
UCECTSPOAP1 →-0.543-1.700.001.00234
SKCMZWINT →+0.626+2.241.001.00534
SKCMUQCRH →+0.530+2.846<.001.00133
SKCMNDUFA6 →+0.533+3.807<.001<.00133
SKCMPRC1 →+0.775+2.163<.001.00933
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,059 associations by consensus.

CBARP by FAM160A2 expression — UCEC

Box plot of CBARP in FAM160A2-low vs FAM160A2-high samples in UCEC.

Explore this box plot interactively →

Exploration