FAM160A2

Across TCGA patient cohorts, FAM160A2 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM160A2-associated genes across cancer lineages are Cyclin-B1, ERK2, and Akt_pT308. Each is linked with FAM160A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM160A2-to-partner and partner-to-FAM160A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by FAM160A2-low versus FAM160A2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160A2→partner) and Y-score (partner→FAM160A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Cyclin-B1 →	+0.598	+2.321	.003	.035	3	2
UCEC	ERK2 →	+0.151	+2.459	.021	.018	3	2
UCEC	Akt_pT308 →	+0.527	+1.807	.014	.024	3	2
UCEC	ATM →	-0.419	-1.794	.006	.024	3	2
UCEC	Caspase-8 →	-0.248	-3.143	.003	<.001	3	2
UCEC	4E-BP1 →	+0.215	+1.514	.020	.015	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Cyclin-B1 by FAM160A2 expression — SKCM

Explore this box plot interactively →