FAM160A2

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM160A2 mutation is significantly associated with the drug of many other genes, with 29 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM160A2-associated genes across cancer lineages are CP724714, Ispinesib Mesylate, and Masitinib. Each is linked with FAM160A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM160A2-to-partner and partner-to-FAM160A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CP724714 grouped by FAM160A2-low versus FAM160A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160A2→partner) and Y-score (partner→FAM160A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECP724714 →+0.353+2.652.035.04532
LARGE_INTESTINEIspinesib Mesylate →+0.764+2.652.018.04531
LARGE_INTESTINEMasitinib →+0.541+2.652.011.04531
LARGE_INTESTINEPF-00299804 →+0.678+2.652.003.04531
LARGE_INTESTINEIWP-2 →+0.285+2.893.032.03421
LARGE_INTESTINEIGF1R_3801 →+0.641+2.649.032.04621
Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

CP724714 by FAM160A2 expression — LARGE_INTESTINE

Box plot of CP724714 in FAM160A2-low vs FAM160A2-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration