FAM160A1

Across TCGA patient cohorts, FAM160A1 mutation is significantly associated with the RNA expression of many other genes, with 753 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM160A1-associated genes across cancer lineages are C17orf98, JAKMIP1, and EOMES. Each is linked with FAM160A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM160A1-to-partner and partner-to-FAM160A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C17orf98 grouped by FAM160A1-low versus FAM160A1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160A1→partner) and Y-score (partner→FAM160A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	C17orf98 →	+0.266	+3.926	<.001	.007	3	2
UCEC	JAKMIP1 →	+0.445	+2.906	.003	.001	3	2
UCEC	EOMES →	+0.388	+1.874	.003	.002	3	2
UCEC	DIS3L →	+0.381	+2.617	.003	.005	3	2
UCEC	ELP5 →	+0.394	+3.764	<.001	<.001	3	2
UCEC	LAG3 →	+1.005	+3.010	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 753 associations by consensus.

C17orf98 by FAM160A1 expression — LIHC

Explore this box plot interactively →