FAM160A1

Across TCGA patient cohorts, FAM160A1 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM160A1-associated genes across cancer lineages are eEF2, eIF4E, and 4E-BP1. Each is linked with FAM160A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM160A1-to-partner and partner-to-FAM160A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by FAM160A1-low versus FAM160A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160A1→partner) and Y-score (partner→FAM160A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.298	+2.999	.029	.035	3	2
UCEC	eIF4E →	+0.167	+2.335	.039	.018	3	2
UCEC	4E-BP1 →	+0.399	+2.614	<.001	.005	3	2
UCEC	14-3-3_beta →	-0.087	-3.432	.024	.005	3	1
UCEC	eIF4G →	+0.329	+2.584	.005	.001	3	1
UCEC	A-Raf_pS299 →	-0.109	-2.087	.017	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

eEF2 by FAM160A1 expression — UCEC

Explore this box plot interactively →