FAM160A1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM160A1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible FAM160A1-associated genes across cancer lineages are ESX1, GJA10, and OR7G3. Each is linked with FAM160A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM160A1-to-partner and partner-to-FAM160A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ESX1 grouped by FAM160A1-low versus FAM160A1-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM160A1→partner) and Y-score (partner→FAM160A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaESX1 →+0.126+4.807<.001.00631
BLOOD_MyelomaGJA10 →+0.023+4.807<.001.00631
BLOOD_MyelomaOR7G3 →+0.886+4.807.001.00631
BLOOD_MyelomaTCP10L3 →+0.056+4.807<.001.00631
BLOOD_MyelomaFOXB2 →+0.020+4.807<.001.00631
BLOOD_MyelomaRPTN →+0.013+4.807<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

ESX1 by FAM160A1 expression — BLOOD_Myeloma

Box plot of ESX1 in FAM160A1-low vs FAM160A1-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration