FAM156B

Across TCGA pan-cancer cohorts, FAM156B RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated FAM156B data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FAM156B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM156B expression acts as an unfavorable survival marker, although some lineages such as BLCA and STAD show a favorable association.

KIRC, UVM, and BRCA are the cancer types where FAM156B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.526	0.701	<.001	72	view →
UVM	OS	Tertile	III,IV	0.231	0.836	.001	42	view →
BRCA	DFS	Tertile	II,III,IV	0.901	0.953	.003	32	view →
LIHC	OS	Tertile	All	0.664	0.809	.009	24	view →
MESO	DFS	Tertile	IV	0.079	0.510	.003	23	view →
BLCA	OS	Median	IV	0.709	0.492	.003	21	view →
READ	OS	Tertile	IV	0.504	0.971	<.001	20	view →
KIRP	DFS	Tertile	IV	0.033	0.459	<.001	18	view →
UCEC	DFS	Quartile	II,III,IV	0.744	0.856	.016	16	view →
TGCT	OS	Quartile	III,IV	0.003	1.000	.008	12	view →
ACC	DFS	Median	All	0.329	0.697	.031	10	view →
STAD	OS	Quartile	II,III,IV	0.742	0.443	.028	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

FAM156B–KIRC (DFS)

Open the KIRC breakdown →