FAM156A

Across TCGA pan-cancer cohorts, FAM156A RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of FAM156A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where FAM156A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM156A is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KIRP, COAD, and HNSC are the cancer types where FAM156A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM156A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	II,III,IV	+0.099	<.001	10	view →
COAD	Male	All	+0.096	<.001	10	view →
HNSC	All	III,IV	+0.048	.001	9	view →
LIHC	All	II,III,IV	+0.047	<.001	8	view →
KIRC	All	All	+0.035	<.001	6	view →
KICH	Female	All	−0.071	<.001	4	view →
BRCA	All	All	−0.038	.012	4	view →
READ	All	III,IV	+0.134	.006	3	view →
CHOL	All	All	+0.118	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

FAM156A–KIRP

Open the KIRP breakdown →