FAM155B

Across TCGA patient cohorts, FAM155B mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM155B-associated genes across cancer lineages are ERK2, EGFR_pY1068, and MEK1. Each is linked with FAM155B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM155B-to-partner and partner-to-FAM155B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by FAM155B-low versus FAM155B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM155B→partner) and Y-score (partner→FAM155B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.201	+1.807	.002	.004	3	3
UCEC	EGFR_pY1068 →	-0.246	-1.514	.004	.015	3	2
UCEC	MEK1 →	+0.307	+2.321	.013	.005	3	2
UCEC	VHL →	-0.913	-2.247	<.001	.001	3	2
UCEC	ATM →	-0.451	-2.687	.003	.005	3	2
UCEC	Caspase-7-cleavedD198 →	+0.487	+2.584	.016	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

ERK2 by FAM155B expression — UCEC

Explore this box plot interactively →