Across TCGA patient cohorts, FAM155A mutation is significantly associated with the RNA expression of many other genes, with 4,596 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM155A-associated genes across cancer lineages are PPIH, RAET1K, and KNL1. Each is linked with FAM155A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM155A-to-partner and partner-to-FAM155A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM155A→partner) and Y-score (partner→FAM155A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	PPIH →	+0.500	+3.219	.003	.009	3	4
UCEC	RAET1K →	+0.406	+3.732	<.001	<.001	3	4
UCEC	KNL1 →	+0.684	+2.914	<.001	.001	3	4
UCEC	RAD51 →	+1.038	+3.534	<.001	<.001	3	4
SKCM	SCML2 →	+0.751	+2.434	.002	.001	3	3
SKCM	DNAJC2 →	+0.554	+3.497	.009	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,596 associations by consensus.

Exploration

FAM155A survival (RNA) · tumor vs normal (RNA) · all FAM155A data types