Across TCGA cell cohorts, FAM155A mutation is significantly associated with the RNA expression of many other genes, with 55 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM155A-associated genes across cancer lineages are HCN4, SPAG11A, and AMELX. Each is linked with FAM155A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM155A-to-partner and partner-to-FAM155A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM155A→partner) and Y-score (partner→FAM155A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HCN4 →	+0.141	+2.900	.001	.002	3	2
SKIN	SPAG11A →	+0.073	+6.022	<.001	.001	3	1
BLOOD_Leukemia	AMELX →	+0.033	+4.539	<.001	.007	3	1
BLOOD_Leukemia	GPR26 →	+0.057	+4.539	<.001	.007	3	1
BLOOD_Leukemia	CST2 →	+0.499	+4.152	<.001	.009	3	1
BLOOD_Leukemia	GPR149 →	+0.014	+5.060	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Exploration

FAM155A survival (RNA) · tumor vs normal (RNA) · all FAM155A data types