FAM153DP

Across TCGA pan-cancer cohorts, FAM153DP RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated FAM153DP data layer compared with 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher FAM153DP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM153DP expression acts as an unfavorable survival marker.

LUSC, OV, and SKCM are the cancer types where FAM153DP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	All	0.298	0.733	.002	54	view →
OV	OS	Tertile	III,IV	0.192	0.325	.008	36	view →
SKCM	DFS	Tertile	III,IV	0.109	0.662	<.001	27	view →
MESO	DFS	Tertile	All	0.099	0.392	.030	27	view →
SARC	DFS	Tertile	All	0.070	0.596	<.001	27	view →
GBM	DFS	Tertile	All	0.071	0.288	.009	18	view →
ACC	DFS	Tertile	II,III,IV	0.226	0.725	.009	18	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

FAM153DP–LUSC (OS)

Open the LUSC breakdown →