FAM153DP

Across TCGA pan-cancer cohorts, FAM153DP Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FAM153DP data layer compared with 7 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher FAM153DP Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM153DP expression acts as an unfavorable survival marker.

CESC are the cancer types where FAM153DP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	All	0.092	0.543	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

FAM153DP–CESC (DFS)

Open the CESC breakdown →