Across TCGA patient cohorts, FAM153CP mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM153CP-associated genes across cancer lineages are JNK2, mTOR_pS2448, and p70-S6K_pT389. Each is linked with FAM153CP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM153CP-to-partner and partner-to-FAM153CP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM153CP→partner) and Y-score (partner→FAM153CP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.308	+2.817	.007	.036	3	1
UCEC	mTOR_pS2448 →	-0.201	-3.000	.019	.037	1	1
UCEC	p70-S6K_pT389 →	-0.252	-3.000	.022	.037	1	1
UCEC	P-Cadherin →	-0.173	-2.986	.038	.037	1	1
UCEC	Annexin-1 →	+0.852	+3.000	.005	.037	1	1
UCEC	Shc_pY317 →	-0.221	-3.000	.011	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

FAM153CP survival (RNA) · tumor vs normal (RNA) · all FAM153CP data types