FAM151A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM151A mutation is significantly associated with the RNA expression of many other genes, with 2,903 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM151A-associated genes across cancer lineages are BCCIP, PIGPP2, and RPL17P19. Each is linked with FAM151A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM151A-to-partner and partner-to-FAM151A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCCIP grouped by FAM151A-low versus FAM151A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM151A→partner) and Y-score (partner→FAM151A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECBCCIP →+0.356+2.467.003.00133
HNSCPIGPP2 →+0.073+4.912.003.00533
HNSCRPL17P19 →+0.124+4.912<.001.00533
LUADRNU6-1273P →+0.462+7.108<.001<.00133
COADMIR6798 →+0.313+4.332<.001.00633
CESCRN7SL457P →+0.161+6.144<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,903 associations by consensus.

BCCIP by FAM151A expression — UCEC

Box plot of BCCIP in FAM151A-low vs FAM151A-high samples in UCEC.

Explore this box plot interactively →

Exploration