FAM151A

Across TCGA cell cohorts, FAM151A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,025 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM151A-associated GO terms across cancer lineages are Positive regulation of synapse maturation, Cellular response to alcohol, and Regulation of protein localization to endoplasmic reticulum. Each is linked with FAM151A in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM151A-to-partner and partner-to-FAM151A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of synapse maturation grouped by FAM151A-low versus FAM151A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM151A→partner) and Y-score (partner→FAM151A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of synapse maturation →	+0.238	+0.111	.001	.002	3	7
PANCREAS	Cellular response to alcohol →	+0.085	+0.080	<.001	<.001	2	7
BONE	Regulation of protein localization to endoplasmic reticulum →	+0.121	+0.097	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein import into nucleus →	+0.092	+0.092	.008	.003	2	7
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.061	+0.087	.008	.001	3	6
BLOOD_Leukemia	Negative regulation of myoblast fusion →	+0.042	+0.067	.003	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,025 associations by consensus.

Positive regulation of synapse maturation by FAM151A expression — LUNG_NSCLC_LUSC

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