FAM151A

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM151A mutation is significantly associated with the drug of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM151A-associated genes across cancer lineages are Mirin, MG-132, and GSK2801. Each is linked with FAM151A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM151A-to-partner and partner-to-FAM151A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mirin grouped by FAM151A-low versus FAM151A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM151A→partner) and Y-score (partner→FAM151A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEMirin →+0.415+2.646.028.04731
BLOOD_LymphomaMG-132 →+0.210+2.814.018.04131
LARGE_INTESTINEGSK2801 →+0.353+2.649.026.04621
LARGE_INTESTINEPFI3 →+0.260+2.646.026.04721
LARGE_INTESTINE50869 →+0.548+2.678.008.03721
LARGE_INTESTINESGC-CBP30 →+0.373+2.649.007.04611
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Mirin by FAM151A expression — LARGE_INTESTINE

Box plot of Mirin in FAM151A-low vs FAM151A-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration