FAM149B1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM149B1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,064 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM149B1-associated genes across cancer lineages are CD40, MLNR, and FUCA2. Each is linked with FAM149B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM149B1-to-partner and partner-to-FAM149B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM149B1 versus CD40 in UCEC, with a Pearson correlation of -0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM149B1→partner) and Y-score (partner→FAM149B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCD40 →-0.755-0.361.002.00631
UCECMLNR →+1.028+0.559<.001.00331
UCECFUCA2 →+1.238+0.681.003.00131
UCECTAX1BP1 →+0.803+0.498.007.00431
UCECHTATIP2 →+1.106+0.420.004.00131
UCECGABRR2 →-0.661-0.538<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,064 associations by consensus.

FAM149B1 vs CD40 — UCEC

Per-sample scatter of FAM149B1 vs CD40 in UCEC (Pearson r = -0.61).

Explore this scatter interactively →

Exploration