FAM149B1

Across TCGA patient cohorts, FAM149B1 mutation is significantly associated with the RNA expression of many other genes, with 1,670 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM149B1-associated genes across cancer lineages are FSCB, LINC02464, and COX6CP3. Each is linked with FAM149B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM149B1-to-partner and partner-to-FAM149B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FSCB grouped by FAM149B1-low versus FAM149B1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM149B1→partner) and Y-score (partner→FAM149B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FSCB →	+0.036	+2.026	.001	.001	3	2
CESC	LINC02464 →	+0.110	+4.812	<.001	.006	3	2
UCEC	COX6CP3 →	+0.164	+2.577	<.001	<.001	3	2
COAD	RPSAP57 →	+0.102	+3.588	<.001	.007	3	2
COAD	MIR190A →	+0.276	+4.917	<.001	.003	3	2
COAD	PSAT1P4 →	+0.310	+3.463	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,670 associations by consensus.

FSCB by FAM149B1 expression — UCEC

Explore this box plot interactively →