FAM13A-AS1

Across TCGA pan-cancer cohorts, FAM13A-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated FAM13A-AS1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher FAM13A-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FAM13A-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and BLCA show a favorable association.

SKCM, BLCA, and KIRC are the cancer types where FAM13A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Quartile	All	0.862	0.708	<.001	64	view →
BLCA	DFS	Median	All	0.698	0.551	.002	63	view →
KIRC	DFS	Median	All	0.502	0.702	<.001	57	view →
CESC	DFS	Median	All	0.760	0.879	.001	50	view →
MESO	OS	Quartile	All	0.709	0.313	<.001	33	view →
KICH	DFS	Quartile	III,IV	0.181	0.885	.002	31	view →
THYM	DFS	Median	III,IV	1.000	0.386	.002	19	view →
PRAD	DFS	Tertile	All	0.717	0.862	<.001	18	view →
ESCA	OS	Median	III,IV	0.548	0.320	.018	13	view →
UVM	DFS	Median	All	0.298	0.858	.017	10	view →
OV	OS	Quartile	IV	0.602	0.989	<.001	10	view →
DLBC	DFS	Median	All	0.607	0.928	.006	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

FAM13A-AS1–SKCM (OS)

Open the SKCM breakdown →