FAM136A

Across TCGA patient cohorts, FAM136A mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM136A-associated genes across cancer lineages are CD8+ Tem, DC, and CD4+ naive T-cells. Each is linked with FAM136A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM136A-to-partner and partner-to-FAM136A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tem grouped by FAM136A-low versus FAM136A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM136A→partner) and Y-score (partner→FAM136A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tem →	+0.005	+5.258	<.001	.029	3	1
UCEC	DC →	+0.027	+2.871	.029	.034	3	1
UCEC	CD4+ naive T-cells →	+0.014	+3.267	<.001	.026	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ Tem by FAM136A expression — UCEC

Explore this box plot interactively →