FAM135A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM135A RNA expression is significantly associated with the protein abundance of many other proteins, with 10,347 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM135A-associated proteins across cancer lineages are HSPA13, SMAP1, and MYO6. Each is linked with FAM135A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM135A-to-partner and partner-to-FAM135A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM135A versus HSPA13 in LSCC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM135A→partner) and Y-score (partner→FAM135A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCHSPA13 →-0.408-0.641.001<.00134
LUADSMAP1 →+0.283+0.522<.001<.00134
LUADMYO6 →+0.519+0.600<.001<.00133
CCRCCPEX1 →+0.208+0.377<.001<.00133
LSCCARHGEF5 →+0.386+0.615<.001<.00133
LSCCPRRC2B →+0.246+0.598<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,347 associations by consensus.

FAM135A vs HSPA13 — LSCC

Per-sample scatter of FAM135A vs HSPA13 in LSCC (Pearson r = -0.35).

Explore this scatter interactively →

Exploration