FAM135A

Across TCGA patient cohorts, FAM135A protein abundance is significantly associated with the RNA expression of many other genes, with 3,855 significant associations in total. OV shows the largest number of these associations.

The most reproducible FAM135A-associated genes across cancer lineages are CASQ1, IQCA1, and GRAP. Each is linked with FAM135A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM135A-to-partner and partner-to-FAM135A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM135A versus CASQ1 in OV, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM135A→partner) and Y-score (partner→FAM135A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CASQ1 →	-0.697	-1.061	.002	<.001	3	3
OV	IQCA1 →	-0.972	-1.072	<.001	.005	3	2
PDAC	GRAP →	-0.466	-1.009	.009	.005	3	2
UCEC	FAM86FP →	-0.751	-0.323	.007	.007	3	2
HNSC	DYNAP →	+0.866	+0.300	.005	.003	3	2
HNSC	EPGN →	+1.259	+0.232	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,855 associations by consensus.

FAM135A vs CASQ1 — OV

Explore this scatter interactively →