FAM135A

Across TCGA cell cohorts, FAM135A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,010 significant associations in total. CNS shows the largest number of these associations.

The most reproducible FAM135A-associated GO terms across cancer lineages are Copper ion export, Regulation of formation of translation preinitiation complex, and Negative regulation of formation of translation preinitiation complex. Each is linked with FAM135A in more than 10 cancer types. Because this analysis shows association rather than direction, both FAM135A-to-partner and partner-to-FAM135A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by FAM135A-low versus FAM135A-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM135A→partner) and Y-score (partner→FAM135A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Copper ion export →	-0.159	-1.176	<.001	<.001	3	11
SKIN	Regulation of formation of translation preinitiation complex →	+0.091	+0.627	.003	.002	3	10
SKIN	Negative regulation of formation of translation preinitiation complex →	+0.091	+0.627	.003	.002	3	10
CNS	Collagen fibril organization →	-0.161	-0.575	.006	.003	3	10
SOFT_TISSUE	Nuclear pore organization →	+0.122	+0.597	<.001	.003	3	9
SOFT_TISSUE	Regulation of centrosome duplication →	+0.063	+0.725	.004	.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,010 associations by consensus.

Copper ion export by FAM135A expression — LARGE_INTESTINE

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