Across TCGA pan-cancer cohorts, FAM131C Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FAM131C data layer compared with 24 for mass-spec protein.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher FAM131C Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM131C expression acts as an unfavorable survival marker.

GBM are the cancer types where FAM131C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Median	All	0.089	0.413	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: FAM131C tumor-vs-normal RNA expression · all FAM131C data types