Across TCGA patient cohorts, FAM131C RNA expression is significantly associated with the protein abundance of many other proteins, with 18,762 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM131C-associated proteins across cancer lineages are UBE2O, PPP1R18, and VASH1_S313. Each is linked with FAM131C in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM131C-to-partner and partner-to-FAM131C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM131C→partner) and Y-score (partner→FAM131C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBE2O →	+0.228	+0.395	<.001	.001	3	5
LSCC	PPP1R18 →	-0.360	-0.564	<.001	<.001	3	4
HNSC	VASH1_S313 →	-0.436	-0.508	<.001	.001	3	4
BRCA	MRTO4 →	+0.403	+0.632	<.001	<.001	3	4
BRCA	SLC3A2 →	+0.585	+0.560	<.001	<.001	3	4
LSCC	ADD2_S592 →	+0.913	+0.501	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,762 associations by consensus.

Exploration

FAM131C survival (RNA) · tumor vs normal (RNA) · all FAM131C data types