Across TCGA patient cohorts, FAM131C mutation is significantly associated with the RNA expression of many other genes, with 330 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM131C-associated genes across cancer lineages are POLR2DP2, SLC25A4, and GPATCH11. Each is linked with FAM131C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM131C-to-partner and partner-to-FAM131C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM131C→partner) and Y-score (partner→FAM131C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POLR2DP2 →	+0.109	+3.582	.007	<.001	3	2
UCEC	SLC25A4 →	+0.630	+3.332	.006	.005	3	1
UCEC	GPATCH11 →	+0.575	+3.332	.003	.005	3	1
UCEC	SEPTIN14 →	+0.535	+2.861	<.001	.009	3	1
UCEC	URM1 →	+0.537	+3.354	.001	.005	3	1
UCEC	DOLPP1 →	+0.627	+3.332	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 330 associations by consensus.

Exploration

FAM131C survival (RNA) · tumor vs normal (RNA) · all FAM131C data types