FAM131C

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM131C mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM131C-associated genes across cancer lineages are FoxM1, Ku80, and PDCD4. Each is linked with FAM131C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM131C-to-partner and partner-to-FAM131C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM131C→partner) and Y-score (partner→FAM131C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECFoxM1 →+0.305+3.000.041.03731
UCECKu80 →+0.424+2.817.001.03631
UCECPDCD4 →-0.737-3.000.006.03731
UCECShc_pY317 →-0.236-3.000.007.03731
UCEC14-3-3_beta →-0.142-2.986.014.03721
UCECTuberin →+0.391+3.000.012.03721
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration