FAM131B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM131B protein abundance is significantly associated with the RNA expression of many other genes, with 6,287 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM131B-associated genes across cancer lineages are SNRPD3, GGT1, and PRODH. Each is linked with FAM131B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM131B-to-partner and partner-to-FAM131B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM131B versus SNRPD3 in GBM, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM131B→partner) and Y-score (partner→FAM131B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSNRPD3 →+0.323+0.355<.001<.00131
GBMGGT1 →+0.161+0.455.002.00231
GBMPRODH →+0.874+0.465<.001<.00131
GBMSEZ6L →+2.413+0.622<.001<.00131
GBMSRRD →+0.438+0.620<.001<.00131
GBMGCAT →+0.634+0.429<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,287 associations by consensus.

FAM131B vs SNRPD3 — GBM

Per-sample scatter of FAM131B vs SNRPD3 in GBM (Pearson r = 0.49).

Explore this scatter interactively →

Exploration