FAM131B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM131B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,383 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FAM131B-associated GO terms across cancer lineages are Vesicle budding from membrane, Respiratory electron transport chain, and Oxidative phosphorylation. Each is linked with FAM131B in more than 9 cancer types. Because this analysis shows association rather than direction, both FAM131B-to-partner and partner-to-FAM131B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle budding from membrane grouped by FAM131B-low versus FAM131B-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM131B→partner) and Y-score (partner→FAM131B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSVesicle budding from membrane →+0.083+1.203<.001<.001310
LUNG_SCLCRespiratory electron transport chain →+0.068+2.103.001<.001310
LUNG_SCLCOxidative phosphorylation →+0.087+1.665<.001.003310
KIDNEYElectron transport chain →+0.058+0.433.007<.00139
LUNG_SCLCNegative regulation of syncytium formation by plasma membrane fusion →+0.085+2.072<.001<.00139
LUNG_SCLCNegative regulation of myoblast fusion →+0.086+1.888<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,383 associations by consensus.

Vesicle budding from membrane by FAM131B expression — CNS

Box plot of Vesicle budding from membrane in FAM131B-low vs FAM131B-high samples in CNS.

Explore this box plot interactively →

Exploration