FAM131B

Across TCGA cell cohorts, FAM131B mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FAM131B-associated genes across cancer lineages are CARTPT, OR5AU1, and FAM9A. Each is linked with FAM131B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM131B-to-partner and partner-to-FAM131B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CARTPT grouped by FAM131B-low versus FAM131B-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM131B→partner) and Y-score (partner→FAM131B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CARTPT →	+0.031	+4.688	<.001	<.001	3	1
SKIN	OR5AU1 →	+0.038	+4.510	<.001	.001	3	1
SKIN	FAM9A →	+0.127	+3.684	<.001	.006	3	1
SKIN	RFX6 →	+0.036	+5.029	<.001	.006	3	1
SKIN	SSX7 →	+0.032	+3.684	<.001	.006	3	1
SKIN	TEX48 →	+0.104	+3.920	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

CARTPT by FAM131B expression — SKIN

Explore this box plot interactively →