FAM131A

Across TCGA cell cohorts, FAM131A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,783 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FAM131A-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of proteasomal ubiquitin-dependent protein catabolic process, and Positive regulation of protein sumoylation. Each is linked with FAM131A in more than 8 cancer types. Because this analysis shows association rather than direction, both FAM131A-to-partner and partner-to-FAM131A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by FAM131A-low versus FAM131A-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM131A→partner) and Y-score (partner→FAM131A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.086	+1.559	<.001	<.001	3	8
OESOPHAGUS	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.053	+0.980	.003	.001	3	8
URINARY_TRACT	Positive regulation of protein sumoylation →	+0.083	+0.993	<.001	.007	3	8
BONE	Internal protein amino acid acetylation →	+0.161	+0.856	<.001	<.001	3	8
OESOPHAGUS	Regulation of autophagosome maturation →	+0.084	+1.041	.008	.009	2	9
KIDNEY	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.049	+1.078	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,783 associations by consensus.

Negative regulation of myoblast fusion by FAM131A expression — BLOOD_Lymphoma

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