FAM131A

Across TCGA cell cohorts, FAM131A mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FAM131A-associated genes across cancer lineages are TNP1, KRT25, and CENPVL1. Each is linked with FAM131A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM131A-to-partner and partner-to-FAM131A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNP1 grouped by FAM131A-low versus FAM131A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM131A→partner) and Y-score (partner→FAM131A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNP1 →	+0.128	+4.415	<.001	.007	3	1
LARGE_INTESTINE	KRT25 →	+0.009	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CENPVL1 →	+0.166	+4.095	.001	.009	3	1
BREAST	OR10K2 →	+0.063	+5.781	<.001	.001	3	1
BREAST	PABPC1L2A →	+0.083	+5.169	<.001	.005	3	1
BREAST	OR10T2 →	+0.183	+5.781	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

TNP1 by FAM131A expression — LARGE_INTESTINE

Explore this box plot interactively →