FAM126A

Across TCGA pan-cancer cohorts, FAM126A mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FAM126A data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FAM126A mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FAM126A expression acts as an unfavorable survival marker.

UCEC, CCRCC, and LSCC are the cancer types where FAM126A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.595	1.000	.005	24	view →
CCRCC	OS	Median	IV	0.451	1.000	.016	13	view →
LSCC	OS	Median	II,III,IV	0.775	1.000	.021	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FAM126A–UCEC (OS)

Open the UCEC breakdown →