FAM126A

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM126A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,955 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FAM126A-associated GO terms across cancer lineages are Peptidyl-lysine oxidation, Negative regulation of cilium assembly, and Positive regulation of focal adhesion assembly. Each is linked with FAM126A in more than 13 cancer types. Because this analysis shows association rather than direction, both FAM126A-to-partner and partner-to-FAM126A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine oxidation grouped by FAM126A-low versus FAM126A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM126A→partner) and Y-score (partner→FAM126A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTPeptidyl-lysine oxidation →+1.263+2.621<.001<.001314
LUNG_NSCLC_LUSCNegative regulation of cilium assembly →+0.096+2.128<.001.002314
BREASTPositive regulation of focal adhesion assembly →+0.165+2.180<.001<.001314
BREASTResponse to oscillatory fluid shear stress →+0.142+2.219<.001<.001314
BREASTCellular response to oscillatory fluid shear stress →+0.142+2.219<.001<.001314
BREASTVascular endothelial cell response to oscillatory fluid shear stress →+0.142+2.219<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,955 associations by consensus.

Peptidyl-lysine oxidation by FAM126A expression — BREAST

Box plot of Peptidyl-lysine oxidation in FAM126A-low vs FAM126A-high samples in BREAST.

Explore this box plot interactively →

Exploration