FAM126A

Across TCGA cell cohorts, FAM126A mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM126A-associated genes across cancer lineages are OR12D3, LCE2A, and IFNA4. Each is linked with FAM126A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM126A-to-partner and partner-to-FAM126A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR12D3 grouped by FAM126A-low versus FAM126A-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM126A→partner) and Y-score (partner→FAM126A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR12D3 →	+0.050	+5.285	<.001	.003	3	1
BLOOD_Leukemia	LCE2A →	+0.071	+5.969	<.001	.001	3	1
BLOOD_Leukemia	IFNA4 →	+0.055	+4.922	<.001	.009	3	1
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1
LARGE_INTESTINE	C6orf118 →	+0.188	+3.793	<.001	.007	3	1
LARGE_INTESTINE	GZMK →	+0.012	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

OR12D3 by FAM126A expression — STOMACH

Explore this box plot interactively →