FAM124B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM124B protein abundance is significantly associated with the RNA expression of many other genes, with 217 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM124B-associated genes across cancer lineages are USP11, FGF9, and NPTX2. Each is linked with FAM124B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM124B-to-partner and partner-to-FAM124B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM124B versus USP11 in LSCC, with a Pearson correlation of 0.97.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM124B→partner) and Y-score (partner→FAM124B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCUSP11 →+0.549+0.750.007.00421
LSCCFGF9 →-0.455-0.750.003.00421
LSCCNPTX2 →+3.020+0.750.002.00421
LSCCMLX →-0.585-0.750.003.00421
LSCCZPR1 →+0.745+0.750.002.00421
LSCCBIRC2 →+1.085+0.750.001.00421
Each partner links to its Q-omics profile. Showing the 6 strongest of 217 associations by consensus.

FAM124B vs USP11 — LSCC

Per-sample scatter of FAM124B vs USP11 in LSCC (Pearson r = 0.97).

Explore this scatter interactively →

Exploration