FAM124B

Across TCGA patient cohorts, FAM124B mutation is significantly associated with the RNA expression of many other genes, with 878 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM124B-associated genes across cancer lineages are RNU6-151P, RNU6-1114P, and RNU6-1304P. Each is linked with FAM124B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM124B-to-partner and partner-to-FAM124B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-151P grouped by FAM124B-low versus FAM124B-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM124B→partner) and Y-score (partner→FAM124B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-151P →	+0.381	+3.486	.002	.002	3	3
LUAD	RNU6-1114P →	+0.364	+4.798	<.001	.006	3	2
LIHC	RNU6-1304P →	+0.617	+5.853	<.001	<.001	3	2
UCEC	PCBP1-AS1 →	+0.494	+2.201	<.001	.009	3	2
UCEC	IGHV3-73 →	+1.670	+2.592	.003	.006	3	2
UCEC	IGHD6-6 →	+0.794	+2.835	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 878 associations by consensus.

RNU6-151P by FAM124B expression — LUSC

Explore this box plot interactively →