FAM124B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM124B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,781 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM124B-associated GO terms across cancer lineages are Regulation of myoblast fusion, Purine ribonucleotide biosynthetic process, and Ribonucleoside triphosphate biosynthetic process. Each is linked with FAM124B in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM124B-to-partner and partner-to-FAM124B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by FAM124B-low versus FAM124B-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM124B→partner) and Y-score (partner→FAM124B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSRegulation of myoblast fusion →+0.040+0.064.003.00635
BLOOD_LeukemiaPurine ribonucleotide biosynthetic process →+0.040+1.111<.001<.00135
BLOOD_LeukemiaRibonucleoside triphosphate biosynthetic process →+0.048+1.158.001<.00135
BLOOD_LymphomaProton transmembrane transport →+0.040+0.249.001.00825
BLOOD_LeukemiaCytoplasmic translation →+0.053+1.555<.001<.00134
BLOOD_LeukemiaRegulation of microtubule nucleation →+0.058+1.013<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,781 associations by consensus.

Regulation of myoblast fusion by FAM124B expression — CNS

Box plot of Regulation of myoblast fusion in FAM124B-low vs FAM124B-high samples in CNS.

Explore this box plot interactively →

Exploration