FAM124B

Across TCGA cell cohorts, FAM124B mutation is significantly associated with the RNA expression of many other genes, with 343 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM124B-associated genes across cancer lineages are CD300H, CDCP2, and HMGXB4. Each is linked with FAM124B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM124B-to-partner and partner-to-FAM124B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by FAM124B-low versus FAM124B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM124B→partner) and Y-score (partner→FAM124B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.020	+3.000	<.001	.003	3	2
LUNG_NSCLC_LUAD	CDCP2 →	+0.020	+4.347	.001	.001	3	1
LARGE_INTESTINE	HMGXB4 →	+0.601	+3.364	.002	.002	3	1
LARGE_INTESTINE	VAPA →	+0.631	+3.364	<.001	.002	3	1
LARGE_INTESTINE	CA2 →	+1.982	+3.087	<.001	.006	3	1
LARGE_INTESTINE	FZD3 →	+0.812	+3.067	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 343 associations by consensus.

CD300H by FAM124B expression — LARGE_INTESTINE

Explore this box plot interactively →