FAM124A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM124A protein abundance is significantly associated with the RNA expression of many other genes, with 1,372 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM124A-associated genes across cancer lineages are LMBRD1, CBLN3, and CDH13. Each is linked with FAM124A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM124A-to-partner and partner-to-FAM124A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM124A versus LMBRD1 in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM124A→partner) and Y-score (partner→FAM124A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVLMBRD1 →+0.612+0.776.001.00132
BRCACBLN3 →-0.945-0.706<.001<.00132
CCRCCCDH13 →+0.767+0.444<.001<.00132
GBMGSN →+0.912+0.499.002.00632
CCRCCVWA1 →+0.865+0.398<.001<.00132
GBMS1PR5 →+0.985+0.412.002.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,372 associations by consensus.

FAM124A vs LMBRD1 — OV

Per-sample scatter of FAM124A vs LMBRD1 in OV (Pearson r = 0.34).

Explore this scatter interactively →

Exploration