FAM124A

Across TCGA patient cohorts, FAM124A mutation is significantly associated with the RNA expression of many other genes, with 540 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM124A-associated genes across cancer lineages are RNU6-858P, BCYRN1, and MIR7974. Each is linked with FAM124A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM124A-to-partner and partner-to-FAM124A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-858P grouped by FAM124A-low versus FAM124A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM124A→partner) and Y-score (partner→FAM124A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-858P →	+0.215	+2.824	.003	.004	3	2
COAD	BCYRN1 →	-0.368	-3.429	.006	.005	3	2
COAD	MIR7974 →	+0.470	+2.233	.001	.002	3	2
PRAD	RNU6-1186P →	+0.253	+7.939	<.001	.008	3	2
UCEC	ABHD3 →	+0.783	+2.828	<.001	.001	3	2
UCEC	SCNN1B →	-1.541	-2.700	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 540 associations by consensus.

RNU6-858P by FAM124A expression — COAD

Explore this box plot interactively →