FAM122B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM122B RNA expression is significantly associated with the protein abundance of many other proteins, with 15,516 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM122B-associated proteins across cancer lineages are CUL4B, STAG2, and TCEAL1. Each is linked with FAM122B in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM122B-to-partner and partner-to-FAM122B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM122B versus CUL4B in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM122B→partner) and Y-score (partner→FAM122B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCUL4B →+0.231+0.607<.001<.00138
COADSTAG2 →+0.305+0.652<.001<.00137
BRCATCEAL1 →+0.753+0.494<.001<.00135
PDACTHOC2_T1443 →+0.559+0.416<.001<.00135
PDACTHOC3 →+0.317+0.400<.001<.00135
LSCCTHOC6 →+0.180+0.516<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,516 associations by consensus.

FAM122B vs CUL4B — LSCC

Per-sample scatter of FAM122B vs CUL4B in LSCC (Pearson r = 0.40).

Explore this scatter interactively →

Exploration