FAM122B

Across TCGA cell cohorts, FAM122B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,984 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM122B-associated GO terms across cancer lineages are Regulation of mitotic cytokinesis, Regulation of chromosome organization, and Regulation of cytokinesis. Each is linked with FAM122B in more than 13 cancer types. Because this analysis shows association rather than direction, both FAM122B-to-partner and partner-to-FAM122B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic cytokinesis grouped by FAM122B-low versus FAM122B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM122B→partner) and Y-score (partner→FAM122B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of mitotic cytokinesis →	+0.130	+0.880	.001	<.001	3	14
BLOOD_Leukemia	Regulation of chromosome organization →	+0.070	+0.668	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of cytokinesis →	+0.090	+1.195	.004	.003	3	14
PANCREAS	Mitotic spindle midzone assembly →	+0.272	+1.185	<.001	<.001	3	12
PANCREAS	Mitotic spindle elongation →	+0.272	+1.185	<.001	<.001	3	12
BLOOD_Leukemia	Negative regulation of cell cycle process →	+0.063	+0.801	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,984 associations by consensus.

Regulation of mitotic cytokinesis by FAM122B expression — PANCREAS

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