Across TCGA cell cohorts, FAM122A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,674 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM122A-associated GO terms across cancer lineages are Negative regulation of heterochromatin organization, Regulation of heterochromatin formation, and Negative regulation of heterochromatin formation. Each is linked with FAM122A in more than 11 cancer types. Because this analysis shows association rather than direction, both FAM122A-to-partner and partner-to-FAM122A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM122A→partner) and Y-score (partner→FAM122A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of heterochromatin organization →	+0.152	+0.960	<.001	<.001	3	12
LUNG_SCLC	Regulation of heterochromatin formation →	+0.172	+0.999	<.001	.002	3	12
LUNG_SCLC	Negative regulation of heterochromatin formation →	+0.152	+0.960	<.001	<.001	3	12
PANCREAS	Positive regulation of mRNA 3'-end processing →	+0.109	+0.734	.001	<.001	3	12
SOFT_TISSUE	Response to aluminum ion →	+0.112	+0.647	<.001	<.001	3	11
BLOOD_Leukemia	Transcription elongation-coupled chromatin remodeling →	+0.088	+0.823	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,674 associations by consensus.

Exploration

FAM122A survival (RNA) · tumor vs normal (RNA) · all FAM122A data types