Across TCGA pan-cancer cohorts, FAM118B Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FAM118B data layer compared with 27 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where higher FAM118B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM118B expression acts as an unfavorable survival marker.

PRAD and LUSC are the cancer types where FAM118B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
LUSC	DFS	Median	All	0.136	0.791	.005	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: FAM118B tumor-vs-normal RNA expression · all FAM118B data types