Across TCGA patient cohorts, FAM118B protein abundance is significantly associated with the RNA expression of many other genes, with 13,087 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM118B-associated genes across cancer lineages are TBCEL, MSANTD2, and TMEM218. Each is linked with FAM118B in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM118B-to-partner and partner-to-FAM118B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM118B→partner) and Y-score (partner→FAM118B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TBCEL →	+0.736	+0.343	<.001	<.001	3	6
HNSC	MSANTD2 →	+0.804	+0.297	.002	<.001	3	5
HNSC	TMEM218 →	+0.598	+0.299	<.001	<.001	3	5
HNSC	SIK2 →	+0.608	+0.305	<.001	<.001	3	5
OV	NFRKB →	+0.871	+0.298	<.001	<.001	3	5
BRCA	FAM234B →	-1.494	-0.276	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,087 associations by consensus.

Exploration

FAM118B survival (RNA) · tumor vs normal (RNA) · all FAM118B data types