Across TCGA patient cohorts, FAM118B mutation is significantly associated with the RNA expression of many other genes, with 2,027 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM118B-associated genes across cancer lineages are RPL17P49, HSPE1P1, and PIGPP3. Each is linked with FAM118B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM118B-to-partner and partner-to-FAM118B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM118B→partner) and Y-score (partner→FAM118B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RPL17P49 →	+0.132	+5.706	<.001	.003	3	2
LUSC	HSPE1P1 →	+0.178	+5.404	<.001	.005	3	2
BLCA	PIGPP3 →	+0.069	+7.640	<.001	.009	3	2
READ	KCND3-AS1 →	+0.293	+5.653	<.001	.003	3	2
UCEC	RNU6-1 →	+0.426	+2.292	.002	<.001	3	2
UCEC	NDUFS5P5 →	+0.145	+1.963	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,027 associations by consensus.

Exploration

FAM118B survival (RNA) · tumor vs normal (RNA) · all FAM118B data types