Across TCGA patient cohorts, FAM118B mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM118B-associated genes across cancer lineages are Caspase-7-cleavedD198, eEF2, and A-Raf_pS299. Each is linked with FAM118B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM118B-to-partner and partner-to-FAM118B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM118B→partner) and Y-score (partner→FAM118B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.948	+2.479	<.001	.010	3	2
UCEC	eEF2 →	+0.637	+3.584	<.001	.002	3	1
UCEC	A-Raf_pS299 →	-0.173	-3.459	<.001	.005	3	1
UCEC	FoxM1 →	+0.236	+2.115	.037	.019	3	1
UCEC	FOXO3a_pS318_S321 →	-0.141	-3.575	.009	.002	3	1
UCEC	GAPDH →	+0.750	+3.459	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Exploration

FAM118B survival (RNA) · tumor vs normal (RNA) · all FAM118B data types