FAM118A

Across TCGA patient cohorts, FAM118A RNA expression is significantly associated with the go_rna of many other GO terms, with 7,168 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible FAM118A-associated GO terms across cancer lineages are Protein modification by small protein removal, Establishment of protein localization to vacuole, and Negative regulation of gene expression, epigenetic. Each is linked with FAM118A in more than 29 cancer types. Because this analysis shows association rather than direction, both FAM118A-to-partner and partner-to-FAM118A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein modification by small protein removal grouped by FAM118A-low versus FAM118A-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM118A→partner) and Y-score (partner→FAM118A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Protein modification by small protein removal →	+0.054	+1.044	<.001	<.001	3	30
STAD	Establishment of protein localization to vacuole →	+0.046	+0.558	<.001	<.001	3	29
SCLC	Negative regulation of gene expression, epigenetic →	+0.127	+1.011	<.001	<.001	2	30
SCLC	Positive regulation of DNA metabolic process →	+0.061	+0.778	<.001	.002	3	29
SCLC	Cytosolic transport →	+0.055	+0.617	<.001	<.001	3	29
UVM	Peptidyl-lysine modification →	+0.045	+1.077	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,168 associations by consensus.

Protein modification by small protein removal by FAM118A expression — UVM

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